Activities

1.     Watch video on toxicokinetic (4:20).

The half life of acetaminophen in therapeutic doses is 2 hours but in overdose it may exceed 12 hours. Use the information in the video to explain why.

2.     Complete this toxidrome game consisting of 5 toxidromes (anticholinergic, cholinergic, opioid, sympathomimetic, sedative-hypnotic) (3 min).

3.     If you would like, an optional reference is available here (1:34 min).

4.     Use the video located here to answer these questions about acetaminophen poisoning (5 min).

a.     What is the major target of organ injury following acetaminophen overdose?

b.     What is the toxic metabolite of acetaminophen?

c.     What is the antidote?

d.     Would you give the antidote to a patient who intentionally overdoses on acetaminophen and has a 4 hour level of 140 mg/dL?

5.     Using the video here, answer the questions below: (10 min)

a.     What makes a drug OTC vs prescription?

b.     What is the difference between a Schedule I drug and a Schedule V drug?

c.     Is this DEA number valid: FZ7344196

d.     Do dietary supplements require a prescription?

Optional: Checkout this article on OTC insulin in Colorado.